科研解读 (Research Digest): 2026-03-08

科研解读 (Research Digest): 2026-03-08

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👋 Welcome to BioF3's Paper Digest! Today's edition features 0 GitHub projects and 4 research papers from bioRxiv, arXiv, and PubMed.

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1. SeekRBP: Leveraging Sequence-Structure Integration with Reinforcement Learning for Receptor-Binding Protein Identification

📄 arXiv Paper | Date: 2026-03-05 | Category: q-bio.GN

Authors: Xiling Luo, Le Ou-Yang, Yang Shen et al.

AI Research Digest (科研解读)

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Motivation: Receptor-binding proteins (RBPs) initiate viral infection and determine host specificity, serving as key targets for phage engineering and therapy. However, the identification of RBPs is complicated by their extreme sequence divergence, which often renders traditional homology-based alig...


2. Spinverse: Differentiable Physics for Permeability-Aware Microstructure Reconstruction from Diffusion MRI

📄 arXiv Paper | Date: 2026-03-04 | Category: q-bio.QM

Authors: Prathamesh Pradeep Khole, Mario M. Brenes, Zahra Kais Petiwala et al.

AI Research Digest (科研解读)

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Diffusion MRI (dMRI) is sensitive to microstructural barriers, yet most existing methods either assume impermeable boundaries or estimate voxel-level parameters without recovering explicit interfaces. We present Spinverse, a permeability-aware reconstruction method that inverts dMRI measurements thr...


3. A tumor-derived lactate/ENO1 lactylation feedback loop facilitates osimertinib resistance of lung adenocarcinoma.

📄 PubMed Article | Date: 2025 Dec 26 | Category: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Authors: Gan L, Sui Q, Xu MD et al.

AI Research Digest (科研解读)

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A tumor-derived lactate/ENO1 lactylation feedback loop facilitates osimertinib resistance of lung adenocarcinoma....


4. Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis.

📄 PubMed Article | Date: 2025 Jun 4 | Category: Journal of advanced research

Authors: He W, Wu J, Wang D et al.

AI Research Digest (科研解读)

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Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis....


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