👋 Welcome to BioF3's Paper Digest! Today's edition features 0 GitHub projects and 4 research papers from bioRxiv, arXiv, and PubMed.
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1. Revisiting the Role of Foundation Models in Cell-Level Histopathological Image Analysis under Small-Patch Constraints -- Effects of Training Data Scale and Blur Perturbations on CNNs and Vision Transformers
📄 arXiv Paper | Date:
2026-03-04| Category:q-bio.QM
Authors: Hiroki Kagiyama, Toru Nagasaka, Yukari Adachi et al.
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Background and objective: Cell-level pathological image analysis requires working with extremely small image patches (40x40 pixels), far below standard ImageNet resolutions. It remains unclear whether modern deep learning architectures and foundation models can learn robust and scalable representati...
2. Dose-Dependent Cardiac Complexity Changes in Children Following Prenatal Glucocorticoid Exposure: Complementary Evidence from Multiscale Entropy Analysis and ECG Foundation Models
📄 arXiv Paper | Date:
2026-03-04| Category:q-bio.QM
Authors: Nicolas B. Garnier, Michelle Dreiling, Valeska Kozik et al.
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\noindent\textbf{Background} Prenatal glucocorticoid exposure alters cardiac development, but whether persistent cardiac effects in childhood follow a dose-response relationship remains unknown. We recently showed that ECG foundation models detect robust cardiac differences between steroid-exposed a...
3. Critical role for a high-plasticity cell state in lung cancer.
📄 PubMed Article | Date:
2026 Jan 21| Category:Nature
Authors: Chan JE, Pan CH, Rub J et al.
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Critical role for a high-plasticity cell state in lung cancer....
4. A tumor-derived lactate/ENO1 lactylation feedback loop facilitates osimertinib resistance of lung adenocarcinoma.
📄 PubMed Article | Date:
2025 Dec 26| Category:Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Authors: Gan L, Sui Q, Xu MD et al.
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A tumor-derived lactate/ENO1 lactylation feedback loop facilitates osimertinib resistance of lung adenocarcinoma....
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